Animal Health and Infectious Diseases

Animal Health and Infectious Diseases

Investigating the healing effects of quadruple spray (allantoin, chlorhexidine, carbomer, boric acid) in third degree burn wounds in rats.

Document Type : Original Article

Authors
1 Department of Veterinary Medicine Karaj Branch Islamic Azad University Karaj Iran
2 Department of surgery and radiology Faculty of veterinary medicine University of tehran
3 DVM graduate, , Faculty of Veterinary Medicine, Islamic Azad University, Garmsar Branch, Garmsar, Iran
4 DVM graduate, , Faculty of Veterinary Medicine, Islamic Azad University, Karaj Branch, Karaj, Iran.
Abstract
Abstract

Background:Many factors can cause damage to the skin.In general,these factors are divided into internal and external categories.Among the internal factors,there are immunological,hereditary, congenital,age, metabolic, hormonal and emotional factors. External factors can also be mentioned as physical,chemical,infectious or biological factors .A wound is defined as any break or break in the skin or mucous membranes, which is caused by physical, chemical or biological factors. In other words, the loss of integrity of the skin or mucous membranes is called a wound.
Materials and Methods: For this study, 24 male rats with a specific weight range were obtained from the laboratory animal breeding center of Razi Institute. The rats were randomly divided into 2 groups of twelve. Group one: the control group of twelve that received no medication other than water and food. Group two: a group of twelve that received a four-component spray, applied daily from a distance of one centimeter at a 45-degree angle to the wound site. The Leohill spray contained the four components in a commercially combined form and was prepared in the required amount.
Results:Based on the results obtained and the investigation of the healing process of the third degree burn wound from this study, the quadruple spray did not work successfully in any of the examined items of the healing process of the third degree burn wound.
Conclusion:In total and by evaluating all the factors, it can be concluded that the quadruple spray does not have an effective effect on the recovery and healing of 3rd degree burn wounds alone
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  • Receive Date 29 September 2024
  • Revise Date 02 November 2024
  • Accept Date 18 January 2025
  • First Publish Date 18 January 2025
  • Publish Date 22 June 2026