Background and Aim: Pemphigus and pemphigoid are medical conditions named after the Greek word for "blister". They have been identified in humans as well as several animals such as horses, dogs, cats, and goats. They are a group of autoimmune disorders characterized by vesicle formation.
Materials and Methods: A 10-month-old female Scottish cat, weighing 2.80 kg referred to the clinic with evidence of skin ulceration hair loss on the scalp, and excessive itching which caused increased anxiety. The cat showed regular eating habits, consumed an adequate amount of food and water, and had normal breathing rate, heart rate, capillary refill time, and body temperature. The cat resided in a restricted urban setting, and the proprietor verified that it had not undergone any surgeries or suffered from any illnesses or allergies related to specific foods or medications since it was born. The blood test showed a slight increase in the neutrophil count. Nonetheless, the infection persisted despite the veterinarian's efforts to treat it with antiparasitic tablets, terbinafine, ketoconazole shampoo, and avermectin over the past two months.
Results and Conclusion: Bullous pemphigoid was verified to be present after a biopsy of the skin lesions and subsequent examination using a light microscope. Appropriate medical care was given, and the regrowth of hair on its skin surface. Histopathology plays a crucial role in diagnosing the etiology of dermatological diseases in small animals.